What is MAPX?
MAP-X (Meltome-assisted profiling of protein complexes) is a method for global profiling of protein complexes and protein-protein interactions from TPP (thermal proteome profiling) data. The R package guides the user from measured protein abundances through reconstruction of melting curves, training of machine learning models and using them to predict protein-protein interactions and to mapping of global maps and local networks to visualize predicted protein interactions and protein complexes.
Installation
You can install the development version of MAPX from GitHub with:
# install.packages("devtools")
devtools::install_github("SamPazicky/MAPX", build_vignettes=TRUE)